| 產品名稱 | JNJ 47965567 |
| 產品貨號 | Axon 2890 CAS [1428327-31-4] MF C28H32N4O2SMW 488.64 Purity: 99% Soluble in DMSO Description Highly potent and brain penetrant P2X7 antagonist in human, rat, and mouse cell lines (pKi values of 7.9, 7.9 and 6.9 for human, rat, and human whole blood P2X7). Probe compound for the preclinical assessment of P2X7 blockade in animal models of neuro-inflammation. DMPK properties suitable for preclinical pharmacodynamics studies. Keywords: JNJ 47965567 | supplier | P2X7 antagonist | JNJ47965567 | JNJ-47965567 | CAS [1428327-31-4] | Non Selective (Cations) | P2X7 | Antagonist | Ion Channels | Brain Penetrant | Neuro-inflammation |
| 產品價格 | 現貨詢價，電話：010-67529703 |
| 產品規格 | |
| 產品品牌 | axonmedchem |
| 產品概述 | |
| 產品詳情 |
JNJ 47965567Axon 2890 CAS [1428327-31-4] MF C28H32N4O2S
DescriptionHighly potent and brain penetrant P2X7 antagonist in human, rat, and mouse cell lines (pKi values of 7.9, 7.9 and 6.9 for human, rat, and human whole blood P2X7). Probe compound for the preclinical assessment of P2X7 blockade in animal models of neuro-inflammation. DMPK properties suitable for preclinical pharmacodynamics studies. Keywords: JNJ 47965567 | supplier | P2X7 antagonist | JNJ47965567 | JNJ-47965567 | CAS [1428327-31-4] | Non Selective (Cations) | P2X7 | Antagonist | Ion Channels | Brain Penetrant | Neuro-inflammation
Potent, brain-penetrant P2X7 antagonist
Chemical nameN-((4-(4-Phenylpiperazin-1-yl)tetrahydro-2H-pyran-4-yl)methyl)-2-(phenylthio)nicotinamide Parent CAS No.[1428327-31-4] |
| 產品資料 |
