| 產品名稱 | Chloroquine diphosphate - NSC 14050 |
| 產品貨號 | Axon 2431 CAS [50-63-5] MF C18H26ClN3.2H3PO4MW 515.86 Purity: 99% Optical purity: Racemate Soluble in water Description Classical antimalarial drug (CQ) with lysosomotropic effects causing necrosis and apoptosis. Inhibitor of hemozoin (β-?hematin) formation in malaria (Plasmodium strains) affected red blood cells. Nowadays, most of the Plasmodium falciparum strains are resistant to this drug. Chloroquine was found to inhibit the human thiamine transporter ThTr-2 (SLC19A3), and to inhibit cell growth and to induce cell death in A549 lung cancer cells. KEYWORDS: Chloroquine diphosphate | supplier | Antimalarial drug | NSC 14050 | NSC14050 | CQ | CAS [50-63-5] | [54-05-7] | beta-hematin | Plasmodium | hemoglobin | hemozoin | thiamine | transporter | ThTr-2 | SLC19A3 | apoptosis | necrosis |
| 產品價格 | 現貨詢價，電話：010-67529703 |
| 產品規格 | |
| 產品品牌 | axonmedchem |
| 產品概述 | |
| 產品詳情 |
Chloroquine diphosphate - NSC 14050Axon 2431 CAS [50-63-5] MF C18H26ClN3.2H3PO4
DescriptionClassical antimalarial drug (CQ) with lysosomotropic effects causing necrosis and apoptosis. Inhibitor of hemozoin (β-?hematin) formation in malaria (Plasmodium strains) affected red blood cells. Nowadays, most of the Plasmodium falciparum strains are resistant to this drug. Chloroquine was found to inhibit the human thiamine transporter ThTr-2 (SLC19A3), and to inhibit cell growth and to induce cell death in A549 lung cancer cells. KEYWORDS: Chloroquine diphosphate | supplier | Antimalarial drug | NSC 14050 | NSC14050 | CQ | CAS [50-63-5] | [54-05-7] | beta-hematin | Plasmodium | hemoglobin | hemozoin | thiamine | transporter | ThTr-2 | SLC19A3 | apoptosis | necrosis
Classical antimalarial drug causing necrosis and apoptosis
Chemical nameN4-(7-chloroquinolin-4-yl)-N1,N1-diethylpentane-1,4-diamine bis(phosphate) Parent CAS No.[54-05-7] |
| 產品資料 |
